Maternity Practice Exam 2026 - Free Maternity Nursing Practice Questions and Study Guide

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In a pregnant client with suspected HIV infection who presents with leukopenia, thrombocytopenia, and anemia, which laboratory test would best confirm HIV?

Serum creatinine

T-lymphocyte determination

HIV primarily attacks CD4-positive T lymphocytes, so the number of T cells in the blood reflects the virus’s impact on the immune system. Measuring T-lymphocyte (CD4) counts directly addresses this effect and, in the setting of suspected HIV with cytopenias, helps confirm HIV-related immune suppression. The other options don’t assess HIV status: serum creatinine looks at kidney function, blood type and crossmatch are for transfusion planning, and erythrocyte sedimentation rate is a nonspecific inflammatory marker. In this context, T-lymphocyte determination best aligns with HIV infection and its clinical presentation.

Blood type and crossmatch

Erythrocyte sedimentation rate